Daily Program
6:00 – 7:15 pm |
Welcome to the 12th Biennial Symposium of the International Eosinophil SocietyChair: Mark Larché, Canada (Scientific Program Chair) |
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6:00 – 6:10 pm |
Welcome from McMaster University |
Paul O’Byrne, Canada |
6:10 – 6:40 pm |
Welcome Lecture: The Clinical Biology of Eosinophils: A Saga |
Judah Denburg, Canada |
6:45 – 7:15 pm |
What have we Learned about Eosinophils and Eosinophilic Disorders from Eosinophil-Targeted Therapeutics |
Gail Gauvreau, Canada |
7:30 – 9:30 pm |
Welcome ReceptionArt Gallery of Hamilton |
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Return to Symposium Homepage
7:00 – 8:00 am8:00 – 10:00 am |
Breakfast with an ExpertSession 1: Regulation of Eosinophil Development |
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8:00 – 8:25 am |
State-of-the-Art: 'Haeckel'ing Evolution of Eosinophils and Function: "Ontogeny Recapitulates Phylogeny"…or Does It? |
Steven Ackerman, USA |
8:25 – 8:45 am |
Cutting-Edge: Metabolic Reprogramming and Stromal Support in Generation of Long-Lived Eosinophils |
Sergejs Berdnikovs, USA |
8:45 – 9:05 am |
Cutting-Edge: Myeloid Progenitor Differentiation Pathways Identified through scRNAseq |
Claus Nerlov, UK |
9:05 – 9:25 am |
Cutting-Edge: Expanding Landscape of Myeloid Neoplasms with Gene Rearrangement and Eosinophilia |
Nives Zimmermann, USA |
9:25 – 9:40 am |
Oral Abstract Presentation |
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9:40 – 9:55 am |
Oral Abstract Presentation |
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10:00 – 10:30 am |
Break |
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10:30 - 12:30 pm |
Session 2: Cell Death (and Stress, Autophagy) in Eosinophil Biology |
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10:30 – 10:55 am |
State-of-the-Art: Regulation of Cell Death and Autophagy |
Hans-Uwe Simon, Switzerland |
10:55 – 11:15 am |
Cutting-Edge: Integration of Cytolysis and Autophagy in Eosinophils |
Stephane Esnault, USA |
11:15 – 11:35 am |
Cutting-Edge: Non-Canonical Siglec-8 Signaling to Eosinophil Cell Death |
Jeremy O’Sullivan, USA |
11:35 – 11:55 am |
Cutting-Edge: Eosinophil Extracellular Traps and Immunothrombosis in EGPA |
Shigeharu Ueki, Japan |
11:55 am – 12:15 pm |
Oral Abstract Presentation |
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12:15 – 12:30 pm |
Oral Abstract Presentation |
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12:30 – 1:00 pm |
IES Business Meeting |
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1:00 – 4:00 pm |
Break |
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4:00 – 5:00 pm |
Paul Ehrlich Award Lecture |
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5:00 – 7:00 pm |
Poster Session 1 |
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7:15 pm |
Networking Event for Young Scientists |
Return to Symposium Homepage
7:00 – 8:00 am |
Breakfast with an Expert |
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8:00 – 10:00 am |
Session 3: Eosinophils and Local Immunity- Interactions with Multiple Cell Types |
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8:00 – 8:25 am |
State-of-the-Art: Eosinophils and Control of Peripheral Nervous Systems |
Matthew Drake, USA |
8:25 – 8:50 am |
State-of-the-Art: Eosinophil Interactions with Mast Cells |
Francesca Levi-Schaffer, Israel |
8:50 – 9:10 am |
Cutting-Edge: Regulation of Eosinophils by ILC2 cells |
Roma Sehmi, Canada |
9:10 – 9:30 am |
Cutting-Edge: Eosinophil and IL-5 Regulation of Plasmacytoid Dendritic Cells |
Michelle Gill, USA |
9:30 – 9:45 am |
Oral Abstract Presentation |
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9:45 – 10:00 am |
Oral Abstract Presentation |
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10:00 – 10:30 am |
Break |
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10:30 - 12:30 pm |
Session 4: Eosinophils in Host Defense |
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10:30 – 10:55 am |
State-of-the-Art: Eosinophils and Host Defense Against Parasites |
De’Broski Herbert, USA |
10:55 – 11:15 am |
Cutting-Edge: Eosinophils and Mycobacterium Tuberculosis Infection |
Katrin Mayer-Barber, USA |
11:15 – 11:35 am |
Cutting-Edge: Eosinophils and Influenza Infection |
Amali Samarasinghe, USA |
11:35 – 11:55 am |
Cutting-Edge: Eosinophils in the context of Aspergillus Fumigatus-Induced Lung Inflammation |
David Voehringer, Germany |
11:55 am – 12:10 pm |
Oral Abstract Presentation |
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12:10 – 12:25 pm |
Oral Abstract Presentation |
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12:30 – 3:30 pm |
Break / Optional Networking Event |
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3:30 – 5:30 pm |
Session 5: Reciprocal Interactions Between Eosinophils and Microbiomes in Homeostasis/Dysbiosis |
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3:30 – 3:55 pm |
State-of-the-Art: Role of Esophageal Microbiome Homeostasis and Eosinophilic Inflammation |
Cathryn Nagler, USA |
3:55 – 4:15 pm |
Cutting-Edge: A Gut Commensal Protozoa Remotely Shapes a Lung Niche for Asthma Promoting Eosinophils |
Arthur Mortha, Canada |
4:15 – 4:35 pm |
Cutting-Edge: Intestinal Eosinophil Heterogeneity, Specialization and Microbial Regulation |
Isabelle Arnold, Switzerland |
4:35 – 4:55 pm |
Cutting-Edge: Eosinophils and Microbial Signals in Asthma |
Donata Vercelli, USA |
4:55 – 5:10 pm |
Oral Abstract Presentation |
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5:10 – 5:25 pm |
Oral Abstract Presentation |
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5:30 – 7:30 pm |
Poster Session 2
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Return to Symposium Homepage
7:00 – 8:00 am |
Breakfast with an Expert |
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8:00 – 10:00 am |
Session 6: Eosinophils and Mast Cells in EGID – CEGIR-Sponsored |
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8:00 – 8:25 am |
State-of-the-Art: Regulation, Role and Plasticity of Eosinophils in EGID |
Marc Rothenberg, USA |
8:25 – 8:45 am |
Cutting-Edge: Role of Mast Cells in EoE and other EGIDs |
Joshua Wechsler, USA |
8:45 – 9:05 am |
Cutting-Edge: Natural History of and Targeted Treatment Options for EGID |
Glenn Furuta, USA |
9:05 – 9:25 am |
Cutting-Edge: The Role of Mast Cells in Eosinophilic Esophagitis Based on Single-Cell Analyses |
Netali Ben-Baruch Morgenstern, USA |
9:25 – 9:40 am |
Oral Abstract Presentation |
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9:40 – 9:55 am |
Oral Abstract Presentation |
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10:00 – 10:30 am |
Break |
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10:30 – 12:30 pm |
Session 7: Eosinophils in Tissue Injury and Repair |
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10:30 – 10:55 am |
State-of-the-Art: Remodeling and Fibrosis in Eosinophil Inflammation |
Seema Aceves, USA |
10:55 – 11:15 am |
Cutting-Edge: Eosinophils Promote Allograft Acceptance in Lung Transplantation |
Alex Mei, USA |
11:15 – 11:35 am |
Cutting-Edge: Eosinophilic Fasciitis-Mouse Models |
Maxime Kinet, USA |
11:35 – 11:55 am |
Cutting-Edge: Eosinophils Protect and Improve Cardiac Function |
Guo-Ping Shi, USA |
11:55 am – 12:10 pm |
Oral Abstract Presentation |
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12:10 – 12:25 pm |
Oral Abstract Presentation |
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12:30 – 3:00 pm |
Break |
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3:00 – 5:00 pm |
Session 8: Eosinophils in Tumor Biology and Cancer Therapy |
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3:00 – 3:25 pm |
State-of-the-Art: The Multifaceted Roles of Eosinophils in the Tumor Microenvironment and Following Cancer Immunotherapy |
Ariel Munitz, Israel |
3:25 – 3:45 pm |
Cutting-Edge: The GM-CSF–IRF5 Signaling Axis in Eosinophils Promotes Antitumor Immunity |
TBA |
3:45 – 4:05 pm |
Cutting-Edge: Eosinophilic Inflammation Promotes CCL6-Dependent Metastatic Tumor Growth |
TBA |
4:05 – 4:25 pm |
Cutting-Edge: Eosinophil Collaborations with Innate Cells: On the Front Foot Against Cancer |
Gabrielle Belz, Australia |
4:25 – 4:40 pm |
Oral Abstract Presentation |
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4:40 – 4:55 pm |
Oral Abstract Presentation |
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5:00 – 5:15 pm |
Break |
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5:15 – 6:15 pm |
Gerald J. Gleich Award Lectures |
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5:15 pm – 5:45 pm |
Eosinophils are an Essential Element of a Type 2 Immune Axis that Controls Thymus Regeneration |
Emilie Cosway, United Kingdom |
5:45 pm – 6:15 pm |
Metastasis-Entrained Eosinophils Enhance Lymphocyte-Mediated Antitumor Immunity |
Sharon Grisaru-Tal, Israel |
7:00 pm |
Networking Dinner and Award CeremonyLiuna Station |
Return to Symposium Homepage
8:00 – 9:25 am |
Session 9: Eosinophils and the Epithelium |
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8:00 – 8:25 am |
State-of-the-Art: Eosinophils in Chronic Rhinosinusitis |
Bob Schleimer, USA |
8:25 – 8:45 am |
Cutting-Edge: Bullous Pemphigoid |
Kyle Amber, USA |
8:45 – 9:05 am |
Cutting-Edge: IgE Autoantibodies in Severe Chronic Spontaneous Urticaria and Atopic Dermatitis |
TBA |
9:05 – 9:25 am |
Cutting-Edge: Eosinophils, Autoimmunity and Mucus Production |
Manali Mukherjee, Canada |
9:30 – 10:00 am |
Break |
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10:00 - 12:00 pm |
Session 10: Pro/Con Debates: What has Targeting Eosinophils with Biologics Taught Us? |
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10:00 am – 11:00 am |
Targeting Eosinophils in Disease is Enough! |
Pro: Amy Klion, USA |
11:00 am – 12:00 pm |
Eosinophils are Dispensable! |
Pro: Gerald Gleich, USA |
12:00 – 1:00 pm |
Lunch |
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1:00 – 2:30 pm |
Session 11: Roundtable Discussions |
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1:00 – 1:45 pm |
Topic 1: Are there Subtypes of Eosinophils? |
Facilitators: |
1:45 – 2:30 pm |
Topic 2: Clinical Biology of Eosinophils: |
Facilitators: |
2:30 – 3:00 pm |
Closing RemarksFlorence Roufosse, Belgium |