December 2025 Webinar

Florence Roufosse, MD, PhD

Dr. Florence Roufosse is Professor of Medicine, Internist and Clinical Immunologist at CUB- Hôpital Erasme, Brussels, and is the Past President of the International Eosinophil Society. She is in charge of a specialized consultation dedicated to diagnosing and treating eosinophil-related conditions, that is integrated in the European Reference Network: EuroBloodNet. She also manages patients with systemic auto-immune and auto-inflammatory conditions.

Besides these clinical activities, Dr. Roufosse leads translational research projects to improve understanding and treatment of lymphocytic variant hypereosinophilic syndrome (HES), and participates in international research efforts to better delineate disease course and treatment responses of HES. She is involved in the design and conduct of international clinical trials evaluating efficacy of novel treatment options in patients with HES and eosinophilic granulomatosis with polyangiitis (EGPA), as well as sub-studies that aim to identify biomarkers and/or disease variants predicting treatment responses.

Amy Klion, MD

Amy D. Klion, MD is a Senior Investigator, head of the Human Eosinophil Section and Deputy Chief of the Laboratory of Parasitic Diseases at the NIH. Her research program includes basic and translational research related to the role of the eosinophil and eosinophil activation in disease pathogenesis. The ultimate goal of her laboratory is to develop novel diagnostic tools and treatment approaches for hypereosinophilic syndromes and other conditions associated with marked eosinophilia, including helminth infection. Dr. Klion is a Fellow of the American Society of Tropical Medicine and Hygiene and a recipient of the Society’s Bailey K. Ashford Medal. She has served on the editorial boards of Blood and the Journal of Allergy and Clinical Immunology and numerous advisory committees and expert panels related to her work on eosinophilic disorders and neglected tropical diseases. She is the author of more than 200 scholarly articles, reviews, and textbook chapters. 

Anna Kovalszki, MD

Anna Kovalszki, MD is an Associate Professor of Medicine and fellowship program director at the University of Michigan Allergy and Clinical Immunology Division. She began her significant interest in eosinophil related disorders in earnest while working alongside Peter Weller, MD at Beth Israel Deaconess Medical Center/Harvard Medical School in Boston. She has seen and managed many patients with eosinophilic disorders as well as taken part in clinical trials and participated in research related endeavors in overall presentation, management, and patient related outcomes. She has also shared her knowledge in eosinophil related disorders by giving talks in academic institutions as well as national and regional settings. She is honored to be invited to present at the IES meeting on a topic she enjoys thinking about and which is constantly evolving.

Gerald J. Gleich, MD

Dr. Gerald J. Gleich was born in Escanaba, Michigan and received his degree in Medicine from the University of Michigan. He obtained Internal Medicine residency training at Philadelphia General Hospital and Jackson Memorial Hospital and was a flight surgeon in the United States Air Force. He received postdoctoral training at the University of Rochester and then established a research laboratory for allergic diseases at the Mayo Clinic and Foundation. At Mayo, he was Professor of Medicine and Immunology, Chair of the Department of Immunology, Distinguished Investigator of the Mayo Foundation, and the George M. Eisenberg Professor of Medicine and Immunology. Presently, he is Professor of Dermatology and Medicine at the University of Utah. Dr. Gleich has had a life-long professional commitment to understanding the eosinophil with a focus on its distinctive granules. He and his colleagues have isolated, characterized, identified the cDNAs and the genes and established assays for measurement and localization of all of the principal granule proteins. These efforts lead to the recognition that eosinophil degranulation with release of cytotoxic and cytostimulatory cationic proteins into tissues is characteristic of eosinophil-associated diseases and to recognition of several novel syndromes. Read more

Gregory Constantine, MD

Gregory Constantine, M.D., is an Assistant Research Physician at NIAID, focusing on eosinophilic disorders
since 2020. He earned his M.D. from the University of Texas Long School of Medicine and completed his
internal medicine residency at Baylor College of Medicine, where he also served as chief resident. Dr.
Constantine completed his allergy and immunology subspecialty training at NIH, where he is core faculty
in the Allergy & Immunology Fellowship Training Program. His research explores sensory mucosal
neuroimmune interactions and environmental impacts on eosinophilic gastrointestinal diseases. He is an
investigator in the Human Eosinophil Section and a site-investigator for CEGIR.