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March 2024 Webinar

Eosinophil Imaging

Wednesday, 20 March 2024
9:30 am - 11:00 am US Eastern / 3:30 pm - 5:00 pm Central Europe

Our live webinars are completely free of charge, we just ask that you register in advance. Webinars are hosted on Zoom and audience members can ask questions using the Q&A feature. Real-time closed captioning is available for those with hearing impairments.

Program

9:30 am – 9:35 am: Welcome
IES President: Marc Rothenberg, MD, PhD - United States

9:35 am – 9:40 am: Opening Remarks
Moderators: Nives Zimmermann, MD - United States & Eva Gruden, PhD - Austria

9:40 am – 9:52 am: Microscopic Imaging of the GI Eosinophil
Presenter: Margaret H. Collins, MD - United States

9:52 am - 9:55 am: Q&A

9:55 am – 10:07 am: Radiolabeled Eosinophil Trafficking in the Lung
Presenter: Neda Farahi, PhD - United Kingdom

10:07 am - 10:10 am: Q&A

10:10 am – 10:22 am: Imaging Activated Eosinophils with Electron Microscopy
Presenter: Rossana Melo, PhD - Brazil

10:22 am - 10:25 am: Q&A

10:25 am – 10:37 am: Using Artificial Intelligence to Identify Eosinophil Disease Features and Improve Treatment Assignment
Presenter: Yonatan Savir, PhD - Israel

10:37 am - 10:40 am: Q&A

10:40 am – 10:52 am: 3-Dimensional Imaging of Eosinophils to Quantify their Location around Airway Nerves in Whole Tissue
Presenter: Alexandra Pincus - United States

10:52 am - 10:55 am: Q&A

10:55 am – 11:00 am: Closing Remarks  
Moderators: Nives Zimmermann, MD - United States & Eva Gruden, PhD - Austria

 

Speakers

Margaret H. Collins, MD

Margaret H. Collins, M.D. is board-certified in Anatomic Pathology and Pediatric Pathology.  She is professor of pathology at University of Cincinnati and a staff pathologist at Cincinnati Children’s Hospital Medical Center.  Dr. Collins specializes in the pathology of pediatric gastrointestinal disease, especially eosinophilic gastrointestinal disorders (EGID), and is a central pathology reviewer for the Consortium of Eosinophilic Gastrointestinal Researchers (CEGIR).

Neda Farahi, PhD

Neda Farahi, PhD, is Senior Research Associate at the Victor-Philip Dahdaleh Heart and Lung Research Institute (University of Cambridge) and College Associate Professor at Downing College, Cambridge. Her research focuses on the role of innate immune cells in respiratory diseases, using translational approaches to understand the fate and function of these cells under physiological and pathological conditions. She was a trainee member of the International Eosinophil Society Board of Directors.

Rossana Melo, PhD

Rossana Melo is a Professor of Cell and Molecular Biology at the Institute of Biological Sciences, Federal University of Juiz de Fora (UFJF), Brazil. She received her PhD and MS in Cell Biology from the UFMG (Brazil), post-doctoral training from Harvard Medical School, and held several visiting scientist positions at Harvard University (BIDMC and Harvard T.H. Chan School of Public Health). Nationally, she has been a distinguished scientist with a research productivity grant from the Brazilian National Research Council (CNPq) for 18 years. Dr. Melo’s lab explores cellular mechanisms underlying inflammation and eosinophil biology. She is a specialist in cellular ultrastructure and has been applying innovative electron microscopy techniques to understand vesicular trafficking, secretion, cell death, and cell-cell interactions by eosinophils. She has also been exploring the microscopic cell world as art for science education. Dr. Melo has published over 140 peer-reviewed articles and authored three books, including the first Atlas entirely focused on “Eosinophil Ultrastructure”. She is a current member of the IES at-large Board of Directors.

Yonatan Savir, PhD

Yonatan Savir is an Associate professor at the Faculty of Medicine at the Technion. The research in his lab is devoted to understanding how age affects the ability of biological systems to carry out functions by taking an interdisciplinary approach using tools from experimental biology (single-cell dynamics and omics) and Engineering (AI, mathematical modeling). He received his Ph.D. in theoretical physics of complex systems from the Weizmann Institute and did his postdoctoral training as an HFSP fellow at Harvard Medical School. He has received many prestigious awards, including the Lee Segal prize for theoretical biology, the Alon fellowship, and the American Federation for Aging Research (AFAR) young investigator award. He has vast experience in harnessing artificial intelligence for health applications, co-founded a few startups, and consults for BioTech companies.

Alexandra Pincus

Alexandra Pincus is a Child Neurology resident at the University of California San Francisco. She completed medical school and her PhD in Neuroscience at Oregon Health & Science University, in the laboratory of Dr. David Jacoby and Dr. Allison Fryer. Her PhD work investigated the underlying mechanisms of nerve dysfunction in asthma, using optogenetic activation to compare airway sensory and parasympathetic nerve changes, and using viral vector-based multicolor labeling to characterize the neurological diversity of parasympathetic ganglia. Her work in animals centers around two eosinophilic asthma models and the interaction of these important immune cells with airway nerves. 

Nives Zimmermann, MD

Nives Zimmermann, M.D. is a physician-scientist at the University of Cincinnati, Ohio, USA. Clinically, she is a pathologist, with focus on hematopathology. Her research focuses on eosinophil- and mast cell-mediated diseases. 

Eva Gruden, PhD

Eva Gruden is a pharmacist that completed her PhD at the Medical University of Graz in Austria with distinction. She investigated new ways to target eosinophil overactivation in an interdisciplinary approach. In addition, she completed a stay abroad under the supervision of Dr. Bruce Bochner at Northwestern University in Chicago, where she further deepened her knowledge of complex animal models, monoclonal antibodies and the biology of eosinophils in mice and humans. She is currently a Postdoctoral researcher at the Department of Pharmacology and is studying the involvement of the endocannabinoid and prostaglandin system in EoE.

Last updated: March 20, 2024

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