Latest Research

Role for Complement C5 in Eosinophilic Inflammation of Severe Asthma.
Dong C; et al

Allergy

Cutaneous ceramide synthesis is dysregulated in pediatric eosinophilic esophagitis
Goleva E; et al

J Allergy Clin Immunol

Eosinophil-derived neurotoxin and eosinophil cationic protein are key molecules for blister formation in bullous pemphigoid
Ito T; et al

J Allergy Clin Immunol

Mouse Th2 cell extracellular vesicles promote eosinophil survival through the surface cytokine cargo IL-3.
Bunn KE; et al

J Allergy Clin Immunol

Mepolizumab to Prevent Exacerbations of COPD with an Eosinophilic Phenotype
Sciurba FC; et al

N Engl J Med

Amphiregulin Mediates Epithelial Cell-Eosinophil Interactions and Amplifies Inflammation in Chronic Rhinosinusitis With Nasal Polyps
Zhao L; et al

Allergy

Transcriptomic profiling of the airway epithelium in COPD links airway eosinophilia to type 2 inflammation and corticosteroid response
Leung C; et al

Eur Respir J

Identification of bronchial epithelial genes associated with type 2 eosinophilic inflammation in asthma
Esnault S; et al

J Allergy Clin Immunol

Expansion of multiple CD4+ T-cell lineages in lymphocytic variant hypereosinophilic syndrome
Anderson CF; et al

J Allergy Clin Immunol

Involvement of IL-13-Induced Dysregulation of BDNF-NTRK2 Pathway in Symptoms of Eosinophilic Esophagitis
Osonoi K; et al

Allergy

Small Proline-Rich Protein 2A Drives Epithelial Remodeling in Eosinophilic Chronic Rhinosinusitis with Nasal Polyps via SAA2 Upregulation
Xie S; et al

J Allergy Clin Immunol

Eosinophil extracellular traps drive T follicular helper cell differentiation via VIRMA-dependent MAF stabilization in bullous pemphigoid
Shen S; et al

J Allergy Clin Immunol

Depletion of eosinophils during sensitization but not challenge phase in mice blocks the development of food allergy early in life
Gao H; et al

J Immunol

Esophageal epithelial Ikkβ deletion promotes eosinophilic esophagitis in experimental allergy mouse model.
Clevenger MH; et al

J Allergy Clin Immunol

Exhaled Nitric Oxide and Sputum Eosinophils Are Complementary Tools for Diagnosing Occupational Asthma.
Doyen V; et al

Allergy

Eosinophilic esophagitis drives tissue fibroblast regenerative programs toward pathologic dysfunction
Jumabay M; et al

J Allergy Clin Immunol

Mepolizumab to Prevent Exacerbations of COPD with an Eosinophilic Phenotype
Sciurba FC; et al 

N Engl J Med

Differential T follicular helper cell phenotypes distinguish IgE-mediated milk allergy from eosinophilic esophagitis in children
Lozano-Ojalvo D; et al

J Allergy Clin Immunol

Long-term Efficacy and Safety of Benralizumab Treatment for PDGFRA-negative Hypereosinophilic Syndrome
Kuang FL; et al

J Allergy Clin Immunol

Depletion of eosinophils during sensitization but not challenge phase in mice blocks the development of food allergy early in life
Gao H; et al

J Immunol

Leptin augments IL-13-induced airway eotaxins and submucosal eosinophilia in obesity-associated asthma
Ingram JL; et al

J Allergy Clin Immunol

Single-cell RNA sequencing of human blood eosinophils reveals plasticity and absence of canonical cell subsets
Rodrigo-Muñoz JM; et al

Allergy

A Distinct Genetic Signature Differentiates Inflamed and Noninflamed Fibrotic Tissues in Eosinophilic Esophagitis Patients
Gueguen E; et al

Allergy

Persistent desmoglein-1 downregulation and periostin accumulation in histologic remission of eosinophilic esophagitis
Hoelz H; et al

J Allergy Clin Immunol

One-food versus 4-food elimination diet for pediatric eosinophilic esophagitis: A multisite randomized trial
Kliewer KL; et al

J Allergy Clin Immunol

Imaging eosinophil secretory granules: From storage containers to active, immune responder organelles
Melo RCN, Rothenberg ME

J Allergy Clin Immunol

CSF1-dependent macrophage support matrisome and epithelial stress-induced keratin remodeling in Eosinophilic esophagitis
Benson TM; et al

Mucosal Immunol

Transcriptomic profiling of the airway epithelium in COPD links airway eosinophilia to type 2 inflammation and corticosteroid response
Leung C; et al

Eur Respir J

The C-type lectin receptor MINCLE interferes with eosinophil function and protective intestinal immunity in Strongyloides ratti-infected mice
Linnemann L; et al

Mucosal Immunol

Salivary Metabolomic Signatures in Pediatric Eosinophilic Esophagitis
Hiremath G; et al

Allergy

Eosinophilia and Adverse Effects of Dupilumab for Respiratory Indications: A Real-World Setting
Li SH; et al

J Allergy Clin Immunol Pract

A molecular basis for milk allergen immune recognition in eosinophilic esophagitis
Dilollo J; et al

J Allergy Clin Immunol 

Dupilumab Use in Patients With Hypereosinophilic Syndromes: A Multicenter Case Series and Review of the Literature
Ezekwe EAD Jr; et al

J Allergy Clin Immunol Pract

Hypereosinophilia and Hypereosinophilic Syndromes: First Findings From a Nationwide Multicenter Cohort
Lefèvre G; et al

Allergy

Identification of bronchial epithelial genes associated with type 2 eosinophilic inflammation in asthma
Esnault S; et al

J Allergy Clin Immunol

Thymic Eosinophils: What Are You Doing Here?
Gatti DM; et al

J Leukoc Biol

Twice-Yearly Depemokimab in Severe Asthma with an Eosinophilic Phenotype
Jackson DJ; et al

N Engl J Med

Spatial adaptation of eosinophils and their emerging roles in homeostasis, infection and disease
Arnold IC; et al

Nat Rev Immunol

Nonepithelial Gene Expression Correlates With Symptom Severity in Adults With Eosinophilic Esophagitis
Kim S; et al

J Allergy Clin Immunol Pract

Tissue-specific inducible IL-33 expression elicits features of eosinophilic esophagitis
Pyon GC; et al

J Allergy Clin Immunol 

Metabolic dysfunction mediated by HIF-1α contributes to epithelial differentiation defects in eosinophilic esophagitis
Ryan S; et al

J Allergy Clin Immunol 

Identification of a Specific Granular Marker of Zebrafish Eosinophils Enables Development of New Tools for Their Study
Herbert M; et al

J Immunol 

Clinical monitoring of eosinophilic esophagitis using the esophageal string test
Chang M; et al

J Allergy Clin Immunol Pract

A multicenter comparative cohort study of severe maculopapular exanthema and drug reaction with eosinophilia and systematic symptoms
Copaescu AM; et al

J Allergy Clin Immunol Pract

PD-1 deficiency impairs eosinophil recruitment to tissue during Trichinella spiralis infection
Liu Y; et al

Cell Rep

Eosinophilic Esophagitis Drives Tissue Fibroblast Regenerative Programs Towards Pathologic Dysfunction
Jumabay M; et al

J Allergy Clin Immunol

Leptin augments IL-13-induced airway eotaxins and submucosal eosinophilia in obesity-associated asthma
Ingram JL; et al

J Allergy Clin Immunol

The C-type lectin receptor MINCLE interferes with eosinophil function and protective intestinal immunity in Strongyloides ratti-infected mice
Linnemann L; et al

Mucosal Immunol

Dupilumab Use in Patients With Hypereosinophilic Syndromes: A Multicenter Case Series and Review of the Literature
Ezekwe EAD Jr; et al

J Allergy Clin Immunol Pract

PD-1 deficiency impairs eosinophil recruitment to tissue during Trichinella spiralis infection
Liu Y; et al

Cell Rep

T_H2 cell compensatory effect following benralizumab treatment for eosinophilic gastritis
Ben-Baruch Morgenstern N; et al

J Allergy Clin Immunol

Multiomics analysis identified IL-4-induced IL1RL1^high eosinophils characterized by prominent cysteinyl leukotriene metabolism
Sunata K; et al

J Allergy Clin Immunol

Interleukin (IL)-1/IL-6-Inhibitor-Associated Drug Reaction With Eosinophilia and Systemic Symptoms (DReSS) in Systemic Inflammatory Illnesses
Saper VE; et al

J Allergy Clin Immunol Pract

Distinct roles of types 1 and 2 interferons in human eosinophil regulation: A multi-omics analysis
Sasaki H; et al

Allergy

Identification of a Specific Granular Marker of Zebrafish Eosinophils Enables Development of New Tools for Their Study
Herbert M; et al

J Immunol

PD-1 deficiency impairs eosinophil recruitment to tissue during Trichinella spiralis infection
Liu Y; et al

Cell Rep

Cluster Analysis Identifies Patients With Severe Eosinophilic Asthma Who Achieve Super-Response and Remission With Mepolizumab
Di Bona D; et al

Clin Exp Allergy

Differential Tfh cell phenotypes distinguish IgE-mediated milk allergy from eosinophilic esophagitis in children
Lozano-Ojalvo D; et al

J Allergy Clin Immunol

Activated eosinophils in early life impair lung development and promote long-term lung damage
Raftery AL; et al

Mucosal Immunol

First-Line Antituberculosis Drug Challenge Reactions in Drug Reaction With Eosinophilia and Systemic Symptoms Syndrome in an HIV Endemic Setting
Porter M; et al

J Allergy Clin Immunol Pract 

Interleukin-5 as a pleiotropic cytokine orchestrating airway type 2 inflammation: Effects on and beyond eosinophils
Buchheit KM; et al

Allergy

Persistent Desmoglein-1 downregulation and Periostin accumulation in histologic remission of Eosinophilic Esophagitis
Hoelz H; et al

J Allergy Clin Immunol

CSF1-dependent macrophage support matrisome and epithelial stress-induced keratin remodeling in Eosinophilic esophagitis
Benson TM; et al

Mucosal Immunol

Eosinophilia and Adverse Effects of Dupilumab for Respiratory Indications: A Real-World Setting.
Li SH; et al

J Allergy Clin Immunol Pract

A multicentre comparative cohort study of severe maculopapular exanthema and drug reaction with eosinophilia and systematic symptoms
Copaescu AM; et al

J Allergy Clin Immunol Pract

Tissue-specific inducible IL-33 expression elicits features of eosinophilic esophagitis
Pyon GC; et al

J Allergy Clin Immunol

Twice-Yearly Depemokimab in Severe Asthma with an Eosinophilic Phenotype
Jackson DJ; et al

N Engl J Med

One-food versus 4-food elimination diet for pediatric eosinophilic esophagitis: A multisite randomized trial
Kliewer KL; et al

J Allergy Clin Immunol

Advancing towards a unified eosinophil signature from transcriptional profiling
Chhiba KD; et al

J Leukoc Biol

Long-Term Clinical and Sustained REMIssion in Severe Eosinophilic Asthma treated with Mepolizumab: The REMI-M study
Crimi C; et al

J Allergy Clin Immunol Pract

Metabolic dysfunction mediated by HIF-1alpha contributes to epithelial differentiation defects in eosinophilic esophagitis
Ryan S; et al

J Allergy Clin Immunol

Association of HLA-B*13:01 with DRESS and HLA-A*31:01 with Eosinophilia in SJS/TEN induced by carbamazepine
Kim HJ; et al

J Leukoc Biol

Stromal cell and B cell dialogue potentiates IL-33-enriched lymphoid niches to support eosinophil recruitment and function during type 2 immunity
Bessell E; et al

Cell Rep

Biologic therapy in rare eosinophil-associated disorders: remaining questions and translational research opportunities
Khoury P; et al

J Leukoc Biol

Long-term durability between parent and child patient-reported outcomes in eosinophilic esophagitis
Martin LJ; et al

J Allergy Clin Immunol

Administration of a bacterial lysate to the airway compartment is sufficient to inhibit allergen-induced lung eosinophilia in germ-free mice
Michael AN; et al

J Leukoc Biol